Suhud, Farida (2015) Uji Aktivitas In-silico Senyawa Baru 1-Benzil-3-benzoilurea Induk dan Tersubstitusi sebagai Agen Antiproliferatif. Jurnal Farmasi Indonesia, 7 (4). pp. 245-251. ISSN 1412-1107
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Abstract
This study deals with designing and molecular docking a novel lead compound 1- benzyl-3-benzoylurea and the substituted compounds as antiproliferative agents. The objective of this study was predicting a more potent antiproliferative agent In order to achieve the goal , the in-silica activity againts 1-UWH receptor was calculated by Molegro Virtual Docker 5 and compared with Hydroxyurea as a reference compound. The result showed that all lead and substituted compounds of 1-benzyl-3-benzoylurea were more potent than Hydroxyurea. It is highly recommended that all lead and substituted compounds of 1-benzyl-3-benzoylurea be synthesized further as antiproliferative agents.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 1-benzyl-3-benzoylurea, designing, molecular docking, antiproliferative agents |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmacy |
| Depositing User: | Eko Setiawan 194014 |
| Date Deposited: | 18 Jul 2016 10:44 |
| Last Modified: | 05 Oct 2016 02:33 |
| URI: | http://repository.ubaya.ac.id/id/eprint/28088 |
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