PENGARUH SUHU TERHADAP STABILITAS 3-O-ETHYL ASCORBIC ACID (EAA) DALAM LARUTAN DAPAR BERBAGAI pH

Fitriani, Endang Wahyu and Gunawan, Ellen and Wulandari, Luh Putu Mega and Angkawijaya, Zusan Sentosa and Avanti, Christina (2015) PENGARUH SUHU TERHADAP STABILITAS 3-O-ETHYL ASCORBIC ACID (EAA) DALAM LARUTAN DAPAR BERBAGAI pH. Jurnal Ilmiah Sains & Teknologi, 9 (1). pp. 31-40. ISSN 0216-1540

[img]
Preview
PDF
PENGARUH SUHU TERHADAP STABILITAS EAA_2015.pdf

Download (737Kb) | Preview

Abstract

Based on their ability, vitamin C can be used as antioxidant to prevent aging process, but vitamin C unstable at high temperatures. Because of the instability,vitamin C has been developed to several derivatives, such as 3-OEthyl Ascorbic Acid ( EAA). EAA is derived from vitamin C with ethyl groups tied to position carbon third and more stable than vitamin C or ascorbic acids in general . This research was conducted to study the kinetics of degradation of EAA in citrate buffer pH 3,00; 4,00; 6,00; 6,50, 9,00 and 10,00 The study is done to study kinetics degradation eaa in citrate buffer pH 3,00; 4,00; 6,00; 6,50, 9,00 and 10,00 which stored at a temperature of 30 , 40 and 55 ° C for 21 days using accelerated stability test . The assay is done by using KCKT at λ maximum of 245 nm . From this research can be concluded that EAA most stable at pH 3,00 with a storage temperature of 30 ° C .

Item Type: Article
Uncontrolled Keywords: EAA {3-0-Ethyl Ascorbic Acid), citrate, pH, temperature, stability
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy > Department of Pharmacy
Depositing User: Eko Setiawan 194014
Date Deposited: 06 Sep 2016 03:17
Last Modified: 06 Sep 2016 08:58
URI: http://repository.ubaya.ac.id/id/eprint/28355

Actions (login required)

View Item View Item