Effectivity comparison of amitriptyline versus gabapentin as neurophatic pain therapy in elderly with type ii diabetes mellitus

Jaya, Made Krisna Adi and Herawati, Fauna (2017) Effectivity comparison of amitriptyline versus gabapentin as neurophatic pain therapy in elderly with type ii diabetes mellitus. International Journal of Current Research, 9 (01). p. 44769. ISSN 0975-833X

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Abstract

Background: system. The incidence of diabetic neuropathy was found more prevalent in elderly (44%) compared to adult (24%). Amitriptyline and Gabapentin are widely used on treatment o There were variations in the results of the studies that have been done related to effectiveness between both drugs, causes the need further research, especially on geriatrics. Objective: Gabapentin for diabetic neuropathic pain in geriatric. Methods: outcome targets were neuropathy pain scale reduction ( Whitney U, and Chi Result: compared to baseline. Comparison head to head at low doses, Amitriptyline showed reduce pain intensity greater than Gabapentin (p < 0.05), while on therapeutic doses show the in efficacy between two drugs (p > 0.05). Conclusion: to Gabapentin.

Item Type: Article
Uncontrolled Keywords: Diabetes Neuropatic Pain, Effectiveness, Amitrptyline, Gabapentin
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy > Department of Pharmacy
Depositing User: Eko Setiawan 194014
Date Deposited: 02 Feb 2017 08:15
Last Modified: 02 Feb 2017 08:15
URI: http://repository.ubaya.ac.id/id/eprint/28846

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