Automatic Gridding for DNA Microarray Image Using Image Projection Profile

Siswantoro, Joko (2010) Automatic Gridding for DNA Microarray Image Using Image Projection Profile. In: The 6th IMT-GT Conference on Mathematics, Statistics and its Applications (ICMSA2010), 3rd to 4th November 2010, Universiti Tunku Abdul Rahman, Kuala Lumpur,.

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Abstract

DNA microarray is powerful tool and widely used in many areas. DNA microarray is produced from control and test tissue sample cDNAs, which are labeled with two different fluorescent dyes. After hybridization using a laser scanner, microarray images are obtained. Image analysis play an important role in extracting fluorescence intensity from microarray image. First step in microarray image analysis is addressing, that is finding areas in the image on which contain one spot using gird lines. This step can be done by either manually or automatically. In this paper we propose an efficient and simple automatic gridding for microarray image analysis using image projection profile, base on fact that microarray image has local minimum and maximum intensity at background and foreground areas respectively. Grid lines are obtained by finding local minimum of vertical and horizontal projection profile. This algorithm has been implemented in MATLAB and tested with several microarray images

Item Type: Conference or Workshop Item (Paper)
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Divisions: Faculty of Engineering > Department of Informatic
Depositing User: Joko Siswantoro
Date Deposited: 29 Nov 2017 01:37
Last Modified: 29 Nov 2017 01:37
URI: http://repository.ubaya.ac.id/id/eprint/31235

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