Jayani, Nikmatul Ikhrom Eka and Kartini, Kartini and Basirah, Nurul (2017) Formulasi dan Uji Antiseptik Sediaan Sabun Cuci Tangan Air Perasan Jeruk Nipis (Citrus aurantifolia). Media Pharmaceutica Indonesiana, 1 (4). pp. 222-229. ISSN 1411-8734
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Abstract
Citrus aurantifolia (lime) is the natural ingredients having potential activity as an antiseptic. This study aimed to formulate a hand wash liquid soap with active ingredients lime juice and to evaluate its antiseptic activity. Three different formulas (Formula I, Formula II and Formula III, with a concentration lime juice 20%, 30% and 40% respectively) were evaluated their visual appearance, pH, density and viscosity. Antiseptics activity test was carried out using the Replica method. The results showed that the lime juice hand wash soap had a transparent, homogeny, pale yellow color, and lime odor. Viscosity and pH of the preparation did not meet the criteria of SNI (National Standard of Indonesia). Moreover, the results showed that an increased of lime juice concentration implied a significant decrease in viscosity and pH of lime juice hand wash. Antiseptic activity test is indicated by the percentage of bacterial reduction (%.) The percentage of bacterial reduction were 61.25% in Formula I, 68.89% in Formula II and 89.06% in Formula III. Statistical evaluation using one-way Anova (α = 0.05) followed by Post Hoc Test using LSD methods showed the percentage of bacterial reduction in three formulas were significantly different compare to the control formula (% reduction of control formula = 35.8). Whereas, when the results were compared to the positive controls, there was no significant difference (% positive control reduction = 71.79).
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Citrus aurantifolia; hand-washing soap; physical characteristics; pH;antiseptic |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmacy |
| Depositing User: | NIKMATUL IKHROM EKA JAYANI |
| Date Deposited: | 28 Jun 2018 08:46 |
| Last Modified: | 24 Mar 2021 15:55 |
| URI: | http://repository.ubaya.ac.id/id/eprint/32585 |
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