Antibiotic preferred option for diarrhea children in a Regional General Hospital in Indonesia

Herawati, Fauna and Pua Upa, Muhamad Satria Mandala and Yulia, Rika and Andrajati, Retnosari (2018) Antibiotic preferred option for diarrhea children in a Regional General Hospital in Indonesia. In: ISM CMID, KONAS PAMKI, NS IARW 2018, 13-14 Oktober 2018, Hotel Bumi Surabaya. (Submitted)

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Children admitted to the hospital not only for infection diagnosis but also noninfection diagnosis. The percentage of children who treated with an antibiotic should be comparable with the percentage of children with infection diagnosis. Diarrhea or acute gastroenteritis is one of common infection diagnosis in hospitalized children. In children with diarrhea, rehydration therapy is the key treatment; zinc supplement to reduce the hospital stay; antibiotic treatment depends on etiology, nutrition and immunological status, and the severity of the disease. Good anamneses and diagnoses needed to differentiate whether antibiotic indicated. This study aimed to evaluate the number of antibiotic use in children's ward generally and for diarrhea indication particularly. There are two phases of observation study: i. the number of antibiotic usage in the year 2016 retrospectively, and ii. the number of antibiotic for diarrhea children in May-December 2017 prospectively. The diagnosis and number of antibiotic use in children's ward in the year 2016 calculated from the patient medical record, retrospectively. The stool culture and number of antibiotic use for children with diarrhea collected prospectively from 21 inpatient children. There are 1476 patient’s medical records in 2016; 828 (56%) patients have the antibiotic prescription. Among 828 patients, there are 132 patients with diarrhea (16%). On average, the defined daily dose per 100 bed days is 45.57; the lowest defined daily dose per 100 bed days is on January (23.18) and the highest is on November (69.95). The stool culture results are Escherichia coli (10 specimens), Serratia odorifera (8 specimens), Burkholderia cepacian (2 specimens), and Pseudomonas aeruginosa (1 specimen). There are six patients which be prescribed ampicillin or metronidazole intravenously. The defined daily dose per 100 bed days for these patients (21 patients from May-December 2017) is 12.10. This study result shows that antibiotic is not indicated for these patients because of i. infection diarrhea by Escherichia coli usually self-limited and low ampicillin effectivity against Escherichia coli, ii. there is none Trichomonas vaginalis, amebiasis, or giardiasis come out from stool culture.

Item Type: Conference or Workshop Item (Poster)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy > Department of Pharmacy
Depositing User: Fauna Herawati 201009
Date Deposited: 03 Oct 2018 02:12
Last Modified: 24 Mar 2021 15:55

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