The Role Of Selenium Micronutrients As Antioxidants In Exposure To E-Cigarette Smoke

Suryadinata, Rivan Virlando and Adriani, Merryana and Martini, Santi and Sumarmi, Sri and Wirjatmadi, Bambang (2019) The Role Of Selenium Micronutrients As Antioxidants In Exposure To E-Cigarette Smoke. Asian Journal Pharmaceutical and Clinical Research (AJPCR), 12 (8). pp. 265-268. ISSN Online - 2455-3891; Print - 0974-2441

Preview	PDF Rivan Virlando_THE ROLE OF SELENIUM MICRONUTRIENTS AS ANTIOXIDANTS.pdf Download (2MB) | Preview
	PDF AJPCR Turnitin.pdf Restricted to Registered users only Download (2MB)

Abstract

Objective: E-cigarette products have resulted in various controversies concerning their posed impacts on health. Some argue that exposure to e-cigarette smoke could improve free radicals in the body; thus, it causes harming impacts on health. Peroral selenium (Se) administration can increase superoxide dismutase (SOD) and glutathione peroxidase (GPx) serving as antioxidants in the body. Methods: This research is an experimental study aiming to analyze the effectiveness of Se to decrease free radical due to exposure to e-cigarette smoke as one of the preventive actions. The research was carried out to male Wistar rats with exposure to e-cigarette smoke and peroral Se intake with different time and duration of administration. Results: Research results showed a decrease of antioxidant SOD and GPx in the administration of exposure to e-cigarette smoke, and they gradually increased after Se administration (p=0.000). Meanwhile, the malondialdehyde level was inversely proportional compared to antioxidant SOD and GPx. Conclusion: Se is a micronutrient that can reduce free radicals due to exposure to e-cigarette smoke through enhancement of antioxidant enzymes such as SOD and GPx.

Item Type:	Article
Uncontrolled Keywords:	Selenium, Malondialdehyde, E-cigarette, Glutathione peroxidase, Superoxide dismutase.
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medical
Depositing User:	Ester Sri W. 196039
Date Deposited:	24 Sep 2019 07:30
Last Modified:	03 Apr 2020 05:29
URI:	http://repository.ubaya.ac.id/id/eprint/36358

Actions (login required)

View Item