Preparation and Metabolic Profiling of Spray Dried Extract of Katuk (Sauropus androgynus)

Yunita, Oeke and Winantari, Agnes Nuniek and Sugiarto, Ricky Permana and Prayitna, Gunawan Sutanto and Hwa, Lie (2018) Preparation and Metabolic Profiling of Spray Dried Extract of Katuk (Sauropus androgynus). In: The 4th International Syposium on Temulawak and Potential Plants for Jamu, 28 August 2018, Bogor. (Submitted)

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Katuk (Sauropus androgynus) leaves have been traditionally used in Indonesia for increasing human breast milk production. In the previous research, katuk leaves have high moisture content, therefore katuk leaves extract were being prepared as spray dried katuk extract (SDKE). The freeze dried leaves were extracted with ultrasonic assisted extraction method using ethanol 80% as a solvent. Then, katuk extract was dried with spray drying method and became into SDKE. To improve the physical characteristics of SDKE, this extract was mixed with mannitol, spray dried lactose (SDL), and crospovidone. Metabolic profiles of SDKE were analysed by densitometry method, while the dried extract was dissolved in a suitable solvent and then spotted on GF254 and the plate was developed using a mixture of n-butanol:acetic acid:water (60:22:1,2). The results showed better physical characteristics, especially on moisture content and flow properties of powders. The metabolic profiles of SDKE showed a similar pattern to its fresh leaves.

Item Type: Conference or Workshop Item (Speech)
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy > Department of Pharmacy
Depositing User: Oeke Yunita, S.Si, M.Si. Apt (1161)
Date Deposited: 16 Oct 2019 04:31
Last Modified: 24 Mar 2021 16:13

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