The Effectiveness of 5% Tea Tree Oil cream, 10% Tea Tree Oil cream, and 5% Permethrin Cream for Scabies Treatment in Pediatric Patients

Liuwan, Chesia Christiani and Listiawan, Muhammad Yulianto and Murtiastutik, Dwi and Ervianti, Evy and Sawitri, Sawitri and Prakoeswa, Cita Rosita Sigit and Astari, Linda and Fitriani, Endang Wahyu and Agusni, Regitta Indira and Zulkarnain, Iskandar (2020) The Effectiveness of 5% Tea Tree Oil cream, 10% Tea Tree Oil cream, and 5% Permethrin Cream for Scabies Treatment in Pediatric Patients. Berkala Ilmu Kesehatan Kulit dan Kelamin – Periodical of Dermatology and Venereology, 32 (3). pp. 200-205. ISSN 25494082

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Abstract

Background: Scabies, an infectious disease caused by Sarcoptes scabiei mites, is still one of the most common skin diseases found in developing countries, including Indonesia. The 5% permethrin cream for scabies treatment has been investigated as having 2–3 time to cure scabies. Tea Tree Oil (TTO) is one of the agents that has been proven to have acaricidal potential as an anti-inflammatory, antibacterial, and antipruritic agent. It has minimal side effects in topical use. Purpose: To evaluate the effectiveness of 5% TTO cream and 10% TTO cream in scabies treatment of pediatric patients. Methods: This was an experimental, analytical study with controlled clinical trial methods, and a double-blind, parallel design comparing 5% TTO cream (treatment 1), 10% TTO cream (treatment 2), with 5% permethrin cream (control) to children with scabies. Result: The 5% TTO cream gave a cure rate of 61.5% and was significantly different from the 5% permethrin cream groups with a p-value = 0.044 in the first week of the study. The 5% permethrin cream gave a cure rate of 15.4%, and the cure rate of 10% TTO cream was 53.8% in the first week of the study. Conclusion: There was a significant difference between the 5% TTO cream and 5% permethrin cream in the first week of the study. The highest and fastest cure rates were found in the 5% TTO cream treatment group.

Item Type:	Article
Uncontrolled Keywords:	scabies, tea tree oil, permethrin, children.
Subjects:	R Medicine > RL Dermatology
Divisions:	Postgraduate Programs > Master Program in Clinical Pharmacy
Depositing User:	ENDANG WAHYU FITRIANI
Date Deposited:	28 Jul 2021 09:55
Last Modified:	10 Sep 2021 03:19
URI:	http://repository.ubaya.ac.id/id/eprint/39857

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