Efektivitas Antivirus Oseltamivir Pada Subjek Covid-19 Dengan Atau Tanpa Penyakit Penyerta Di Puskesmas Arut Selatan – Pangkalan Bun

Ardiani, Soufia and Rahem, Abdul and Purnamayanti, Anita (2022) Efektivitas Antivirus Oseltamivir Pada Subjek Covid-19 Dengan Atau Tanpa Penyakit Penyerta Di Puskesmas Arut Selatan – Pangkalan Bun. Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan, 7 (2). pp. 251-260. ISSN 2502-647X; e-ISSN: 2503-1902

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Abstract

Arut Selatan menempati posisi tertinggi dengan 51,55% dari total kasus COVID-19 di Kabupaten Kota Waringin Barat, Kalimantan Tengah. Tujuan penelitian mengetahui karakteristik subjek dan menganalisis efektivitas oseltamivir pada subjek COVID-19. Desain penelitian adalah studi observasional dan pengumpulan data secara retrospektif. Kriteria inklusi adalah subjek COVID-19 dengan atau tanpa penyakit penyerta dan pengobatan rawat jalan di Puskesmas Arut Selatan Pangkalan-Bun yang diberi Oseltamivir. Parameter efektivitas terapi diukur dengan Skala Perkembangan Klinis WHO terdiri dari 5 tingkat kondisi klinis subjek dengan rentang skor 0 (tidak terinfeksi) – 10 (meninggal). Analisis data secara deskriptif dikelompokkan menurut skor skala perkembangan klinis. Hasil penelitian dari 107 subjek terbanyak berjenis kelamin laki-laki (56,1%) dan umur 26-45 tahun (34,6%). Hasil klinis terapi adalah 0,9% subjek sembuh dengan hasil swab negatif (Skala Perkembangan Klinis WHO skor 0), 98,2% membaik (Skor 1), dan 0,9% meninggal (skor 10). Tidak terdapat subjek yang perlu dirujuk ke rumah sakit. Subjek yang mengalami perbaikan klinis, bebas gejala, dan hasil swab negatif terbanyak menjalani karantina mandiri selama 8-15 hari (89,7% subjek). Disimpulkan oseltamivir efektif untuk subjek Covid-19 ringan di Arut Selatan, Pangkalan-Bun, Kota Waringin, Kalimantan Tengah. South Arut occupies the highest position with 51.55% of the total COVID-19 cases in Kota Waringin Barat, Central Borneo. The purpose of the study was to determine patient characteristics and analyze the effectiveness of oseltamivir in COVID-19 patients. The research design was an observational study and data collected retrospectively. Inclusion criteria were COVID-19 subjects with or without comorbidities and outpatient treatment at the Arut Selatan, Pangkalan-Bun Health Center who were given Oseltamivir. Parameters of therapeutic effectiveness were measured by the WHO Clinical Progression Scale consisting of 5 levels of clinical condition of patients with a score range of 0 (uninfected) – 10 (died). Data analysis was descriptively grouped according to clinical progression scale scores. The results of the study of 107 subjects were mostly male (56.1%) and aged 26-45 years (34.6%). The clinical results of therapy were 0.9% of subjects recovered with negative swab results (score 0), 98.2% improved (score 1), and 0.9% died (score 10). There were no subjects who needed to be referred to the hospital, Selfquarantine of 8-15 days showed 96 (89.7%) subjects experienced clinical improvement, symptoms free, and swab results were negative. It could be concluded that oseltamivir was effective for mild Covid-19 subjects in South Arut, Pangkalan Bun, Kota Waringin, Central Borneo.

Item Type:	Article
Uncontrolled Keywords:	Antivirus, Oseltamivir, Covid-19 derajat ringan
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	Ester Sri W. 196039
Date Deposited:	02 Jan 2023 06:12
Last Modified:	02 Jan 2023 06:12
URI:	http://repository.ubaya.ac.id/id/eprint/43032

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