Formulation of Chewable Gummy Tablet of Moringa oleifera L. Leaf Extract Using Combination Kappa Carrageenan and Iota Carrageenan

Gemilang, Nabilaberty Prisma and Jayani, Nikmatul Ikhrom Eka and Rani, Karina Citra (2022) Formulation of Chewable Gummy Tablet of Moringa oleifera L. Leaf Extract Using Combination Kappa Carrageenan and Iota Carrageenan. In: Natural Resources and Life Sciences 2022, 24-25 August 2022, Faculty of Biotechnology, University of Surabaya. (Submitted)

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Abstract

Moringa leaves were the most commonly used part of the Moringa plant because they were rich in nutrients. Moringa leaves extract was developed into a chewable gummy tablet to improve its acceptability. The main component of the chewable gummy tablet was a gelling agent. This study aims to determine the effect of gelling agent ratio (kappa-carrageenan and iota-carrageenan) on the physical characteristics of the chewable gummy tablet. Furthermore, this study was also conducted to determine the optimum formula for a chewable gummy tablet and analyze the physical stability of the prepared formula during storage. In this study, the concentration of gelling agents was 2%. The formulas were developed in this study using the various ratio of kappa-carrageenan and iota-carrageenan 1:0 (control formula), 1:1 (formula 1), 2:1 (formula 2), and 3:1 (formula 3). The results showed that the ratio of kappa-carrageenan and iota-carrageenan determined the texture, disintegration time, swelling ratio, and syneresis. The most optimum formula was Formula 1 (1:1). The characteristics of this formula were a yellow color, melon odor, sweet taste, square shape, chewy texture, the average weight was 2.86 g ± 0.02, the disintegration time was 7.47 min ± 0.02, the swelling ratio was 1.21% ± 0.20, and the syneresis percentage was 0.93 ± 0.11 %. The result of physical stability evaluation during 14 days of storage also revealed that formula 1 was the most stable.

Item Type:	Conference or Workshop Item (Speech)
Uncontrolled Keywords:	Chewable gummy tablets, Moringa oleifera, Kappa Carrageenan, Iota Carrageenan
Subjects:	R Medicine > RS Pharmacy and materia medica R Medicine > RZ Other systems of medicine
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	KARINA CITRA RANI
Date Deposited:	27 Feb 2023 02:00
Last Modified:	27 Feb 2023 02:00
URI:	http://repository.ubaya.ac.id/id/eprint/43494

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