Swiss-Cheese Model Kausalitas Efek Samping Obat: Laporan Kasus Perdarahan Saluran Cerna Pada Penggunaan Obat Herbal

HY, Jefman Efendi Marzuki and Christy, Glorianna and Shofa, Nyimas Maida (2023) Swiss-Cheese Model Kausalitas Efek Samping Obat: Laporan Kasus Perdarahan Saluran Cerna Pada Penggunaan Obat Herbal. Keluwih: Jurnal Kesehatan dan Kedokteran (December), 5 (1). pp. 20-25. ISSN 2715-6419

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Abstract

Pharmacovigilance is a process to identify, evaluating, comprehending, and avoiding harmful drug or treatment-related events. Unfortunately, Indonesia still has a relatively low rate of reporting adverse drug reactions (ADR), including those caused by herbal medications. Lack of information is one factor contributing to this, among others being ignorance and lack of awareness. The Swiss-cheese model is a risk analysis approach that can be used to examine variables that could contribute to the occurrence of adverse drug reactions. A woman, 72, was checked into the hospital after complaining of melena. The patient had previously used herbal product that containing of Retrofracti fructus, Languatis rhizoma, Piperis nigri fructus, Blumeae folium, and Orthosiphonis folium, patient also consume herbs that made from lemongrass (Cymbopogon citratus) dan turmeric (Curcuma longa). Some herbs may have an impact on the cyclooxygenase (COX) system, raising the danger of gastrointestinal problems including bleeding. Diverse patient comorbidities may potentiate adverse drug reactions, necessitating careful monitoring of medication side effects, encompassing both pharmaceutical and herbal remedies. Swiss-cheese model is an approach that can be used to analyze factors that can contribute to adverse drug event. Naranjo and WHO-UMC were used in the causality analysis.

Item Type:	Article
Uncontrolled Keywords:	herbs; adverse drug reaction, gastrointestinal bleeding, patient safety, pharmacovigilans, obat herbal, efek samping, perdarahan saluran cerna, keamanan pasien, farmakovigilans
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medical
Depositing User:	Ester Sri W. 196039
Date Deposited:	17 Jan 2024 04:25
Last Modified:	17 Jan 2024 04:25
URI:	http://repository.ubaya.ac.id/id/eprint/45720

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