Qualitative Analysis For Illicit Drugs And NPS (New Psychoactive Substances) Using GC-MS

Putra, Galih Satrio and Sumari, Sumari and Sulistyowaty, Melanny Ika and Handayani, Magdalena Sri and Suhud, Farida and Kesuma, Dini and Anwari, Farida (2024) Qualitative Analysis For Illicit Drugs And NPS (New Psychoactive Substances) Using GC-MS. Bulletin of Pharmaceutical Sciences (Assiut University), 47 (1). pp. 249-259. ISSN 1110-0052; E-ISSN 3009-7703

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Abstract

This research aims to analyze 500 samples for illicit drugs and NPS (New Psychoactive Substances) using GC-MS (Gas Chromatography Mass Spectrometry) in East Java Indonesia. Sample analysis was carried out by GC-MS with HP-5 column, injection port temperature of 250°C. Column temperature was maintained at 100°C for 2 minutes. It was then raised from10°C/minute to 280°C and maintained for 5 minutes Based on the results, it was detected 244 (48.8 %) Methamphetamine (MA); 30 (6 %) 3,4-Methylenedioxymethamphetamine (MDMA); 44 (8.8 %) 3,4-Methylenedioxyethylamphetamine (MDA); 56 (11.2 %) 3,4- Methylenedioxyethylamphetamine (MDEA); 106 (21.2 %) AB-Fubinaca; 5 (1.0 %) Tramadol; 5 (1.0 %) Ketamine; and 10 (2.0 %) Mephedrone. The identification of illicit drugs and NPS in confiscated materials was successfully achieved via GC-MS. The availability of GC-MS libraries is of great assistance in the identification of new drugs. Alternatively, the study of characteristic molecule fragments combined with the determination of their accurate masses can be a useful approach to identify unknown samples that were not previously analyzed.

Item Type:	Article
Uncontrolled Keywords:	Qualitative Analysis, illicit drugs, NPS, GC-MS
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	Ester Sri W. 196039
Date Deposited:	05 Jun 2024 03:54
Last Modified:	05 Jun 2024 03:54
URI:	http://repository.ubaya.ac.id/id/eprint/46495

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