Plantago major synthesized silver nanoparticles in an anti-acne facial sheet mask: physical stability, safety, and efficacy

Avanti, Christina and Muftilana, Aprilian and Fiesta, Bella and Rani, Karina Citra and Sukweenadhi, Johan and Kartini, Kartini and Mago, Ricky Gonzali and Devi, Wahyu Vinovia and Wulansari, Devyani Diah and Kirtishanti, Aguslina (2024) Plantago major synthesized silver nanoparticles in an anti-acne facial sheet mask: physical stability, safety, and efficacy. Journal of Applied Biology and Biotechnology, 12 (5). pp. 161-169. ISSN 2455-7005, E-ISSN 2347-212X

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Abstract

This study explores a novel approach to treat acne using silver nanoparticles (AgNPs) synthesized from Plantago major (Pm). We aimed to create a stable, safe, and effective anti-acne sheet mask. AgNPs were synthesized using water extracts of Pm leaves and formulated into an anti-acne sheet mask. The sheet mask was assessed for physical stability through freeze-thaw cycling tests and evaluated for safety through dermal irritation tests. The efficacy was assessed on the sheet mask’s impact on Propionibacterium acnes bacteria and inflammation. The anti-acne sheet mask containing AgNPs synthesized from Pm was found to be physically stable and safe for use, with no significant skin irritation observed. The formulation exhibited effective inhibition of P. acnes, particularly in the formula containing only AgNPs. In addition, the sheet mask preparations demonstrated substantial anti-inflammatory activity. The anti-acne sheet mask containing AgNPs synthesized from Pm exhibited favorable safety profile, inhibited P. acnes bacteria, and possessed anti-inflammatory properties.

Item Type:	Article
Uncontrolled Keywords:	Anti-acne, Sheet mask, Silver nanoparticles, Plantago major, Safety, Efficacy
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	Ester Sri W. 196039
Date Deposited:	29 Aug 2024 06:59
Last Modified:	29 Aug 2024 06:59
URI:	http://repository.ubaya.ac.id/id/eprint/47021

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