Bacterial and antibiotic susceptibility test patterns and quality of life of diabetic foot ulcer patients

Yulia, Rika and Pusparisa, Heryanti and Hasan, Farid Al and Herawati, Fauna (2025) Bacterial and antibiotic susceptibility test patterns and quality of life of diabetic foot ulcer patients. Journal of Advanced Pharmaceutical Technology & Research, 16 (4). pp. 195-200. ISSN 2231-4040; E-ISSN 0976-2094

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Abstract

Antibiotic resistance is a growing concern in the treatment of diabetic foot ulcers. To address this, this study analyzed antibiotic usage patterns, microbial profiles, antimicrobial susceptibility, and patient quality of life (QoL). This was a descriptive observational study. This study collected data prospectively at Bojonegoro Regional Hospital between October 2022 and January 2023. Of the 66 patients, all of them exhibited bacterial growth. Microbial sensitivity profiles were categorized as gram‑positive in 21 patients (32%), gram‑negative in 38 patients (58%), gram‑positive ‑ gram‑positive in 1 patient (2%), gram‑negative ‑ gram‑negative in 2 patients (3%), and gram‑positive ‑ gram‑negative in 4 patients (5%). The use of antibiotics is sensitive to gram‑positive drugs, such as: cefepime, ceftriaxone, imipenem, and meropenem. Levofloxacin and imipenem both work 100% in gram‑negative bacteria. Antibiotic usage overall is 159.05 DDD/100 patient days. Of the 11 highest domains, 33 patients (50.0%) have a good QoL, while 19 patients (28.8%) have poor QoL. A comprehensive approach is necessary for the effective management of diabetic foot wound infections, and family support is essential for the improved patient’s QoL.

Item Type:	Article
Uncontrolled Keywords:	Antibacterial agents, behavior, diabetic foot, disease susceptibility, patients, quality of life
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	Ester Sri W. 196039
Date Deposited:	20 Oct 2025 09:03
Last Modified:	20 Oct 2025 09:03
URI:	http://repository.ubaya.ac.id/id/eprint/49726

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