Effectiveness of cyclopentolate 1% compared to the combination of cyclopentolate 1%, tropicamide 1%, and phenylephrine 10% in cycloplegic refractive examination

Fitriyani, Marina Dewi and Boengas, Sawitri and HY, Jefman Efendi Marzuki and Gumilang, Saraswati Retno (2025) Effectiveness of cyclopentolate 1% compared to the combination of cyclopentolate 1%, tropicamide 1%, and phenylephrine 10% in cycloplegic refractive examination. Journal of Clinical Ophthalmology and Research, 13 (4). pp. 484-488. ISSN 2320-3897; E-ISSN 2320-3900

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Abstract

Context: Refractive errors in children require appropriate eyeglass correction. Cycloplegic refraction is a method used to determine eyeglass prescriptions in children due to their high accommodative power. Drugs such as cyclopentolate, tropicamide, and phenylephrine are often used in performing cycloplegic refraction. Aims: This study aims to compare the effectiveness of cyclopentolate 1% (C) and a combination of cyclopentolate 1%, tropicamide 1%, and phenylephrine 10% (CTP). Settings and Design: This is a cross‑sectional study using medical records from using medical records from a private hospital in Surabaya, Indonesia, obtained through consecutive sampling (January 2021– July 2024). Subjects and Methods: Subjects were grouped based on the agents used, C and CTP. Refractive values before and after drug administration, as well as the differences, were compared. Statistical Analysis Used: Data were analyzed using Jamovi 2.4.11. Results: The data obtained were from children aged 6–17 years. Of the 64 samples, 34 (53.1%) were female, and 30 (46.9%) were male. The most common age group was 6–9 years (60.9%). Significant differences in refraction were found before and after drug administration in both the C group (P < 0.05) and the CTP group (P < 0.05). However, no significant differences in refraction were found between the two groups after drug administration for both the left eye (P = 0.21) and the right eye (P = 0.88). Conclusions: There were significant differences in the changes in refraction results in both groups, while no differences in effectiveness were found between the two groups.

Item Type:	Article
Uncontrolled Keywords:	Cyclopentolate, mydriatics, phenylephrine, refractive errors, tropicamide
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medical
Depositing User:	Ester Sri W. 196039
Date Deposited:	05 Jan 2026 08:49
Last Modified:	05 Jan 2026 08:49
URI:	http://repository.ubaya.ac.id/id/eprint/50005

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