DRUG CHOICE PROBLEM STUDY IN HOSPITALIZED HEPATIC CIRRHOSIS PATIENT Dr. RAMELAN NAVY HOSPITAL

Lorensia, Amelia and ., Widyati and Hubeis, A. Aziz. and Bagijo, Hary (2010) DRUG CHOICE PROBLEM STUDY IN HOSPITALIZED HEPATIC CIRRHOSIS PATIENT Dr. RAMELAN NAVY HOSPITAL. In: The 10th Asian Conference On Clinical Pharmacy, 09 - 12 July 2010, Grand Copthorne Waterfront Hotel.

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Abstract

Cirrhosis is a late stage of hepatic fibrosis that has resulted in widespread distortion of normal hepatic architecture. Cirrhotic liver changes in pathophysiology such as reduction in liver blood flow, decrease some metabolic and synthetic function of the liver. Also there is a change in endothelial lining from hepatic sinusoid. These changes result in some consequences that are increase in drugs sensitivity and adverse events due to pharmacokinetic and pharmacodynamic influences.The inappropriate use of prescription drugs in cirrhosis may cause unnecessary adverse drug reactions that can lead to subtle deterioration of function or precipitate medical crises resulting in hospitalization or death.

Item Type: Conference or Workshop Item (Poster)
Uncontrolled Keywords: drug interaction; hepatic cirrhosis
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Pharmacy > Department of Pharmacy
Depositing User: Eko Setiawan 194014
Date Deposited: 22 May 2012 02:45
Last Modified: 22 May 2012 02:45
URI: http://repository.ubaya.ac.id/id/eprint/506

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