Synthesis of Soluble Carboxymethyl Chitosan from Low MolecularWeight of Chitosan

Suseno, Natalia and Padmawijaya, Karsono Samuel and Nico, C.L. and ., Harry (2018) Synthesis of Soluble Carboxymethyl Chitosan from Low MolecularWeight of Chitosan. Prosiding Seminar Nasional Teknik Kimia “Kejuangan”: Pengembangan Teknologi Kimia untuk Pengolahan Sumber Daya Alam Indonesia. K19 - 1-K19 - 5. ISSN 1693-4393

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Carboxymethyl chitosan was obtained under heterogeneous conditions as a product of the reaction of chitosan and monochloroacetic acid in the presence of sodium hydroxide. In the previous experiment, showed that the solubility of carboxymethyl chitosan increased with the decreased of molecular weight of chitosan. However, the solubility of carboxymethyl chitosan in water and acid solvent were still necessary to be maximized. In this experiment aims to determine the effect of condition process such as NaOH concentration, mass ratio chitosan to monochloroacetic acid, and time eterification towards degree of substitution (DS) and the solubility of carboxymethyl chitosan. Some variables that were used to synthesize carboxymethyl chitosan were concentrations of sodium hydroxide (20-50 %w/v), etherification times (1-4 hr), and mass ratio chitosan to monochloro acetic (1:1, 2:1 and 1:2 (v/v). Characterization performed on the synthesized carboxymethyl chitosan including FTIR, degree of substitution (DS), and solubility properties. The solubility of carboxymethyl chitosan increased almost linearly with increasing concentration and etherification times. The maximum DS value being obtained for carboxymethyl chitosan sample synthesized in 50% (w/v) sodium hydroxide with 4-hour reaction and temperature at 60oC, that is 1.79 and solubility of carboxymethyl chitosan were 86.3%; 95.2%; 92.3% in water, 1% of HCl and 1% of CH COOH respectively.

Item Type: Article
Uncontrolled Keywords: low molecular weight of chitosan, NaOH, monocloroacetic acid carboxymethyl chitosan
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Engineering > Department of Chemical Engineering
Depositing User: Ester Sri W. 196039
Date Deposited: 23 Jul 2018 02:01
Last Modified: 23 Jul 2018 02:01

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