Selection of potential Indonesian plant species for antioxidant

Kartini, Kartini and Setiawan, Finna and Sukweenadhi, Johan and Yunita, Oeke and Avanti, Christina (2020) Selection of potential Indonesian plant species for antioxidant. In: The 3rd International Conference on Biosciences, 8 agustus 2019, IPB international Convention Centre, Bogor, Indonesia.

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Diabetic foot ulcer (DFU) is commonly complication of diabetes mellitus. Antimicrobial and antioxidant herbs can be used as complementary therapy in DFU and these properties will be strengthened by silver nanoparticles (AgNPs). This study was performed for screening of Indonesian herbs promising as antioxidant which can be subsequently involved in the green synthesis of AgNPs. Antioxidant of eight herbs extracts were evaluated using 1,1diphenyl-2-picrylhydrazyl method. Their total group of compounds were quantified as well. Phyllanthus niruri and Orthosiphon stamineus exhibited the strongest antioxidant power with IC50 of 102 and 133 µg/ml, followed by Curcuma domestica, Stelechocarpus burahol, and Curcuma xanthorriza with the IC50 of 363, 481, and 540 µg/ml, respectively. Sonchus arvensis, Apium graveolens, Centella asiatica did not have antioxidants activity. Total phenolics from the highest is: O. stamineus > C. domestica > C. xanthorrizha > P. niruri > S. burahol > S. arvensis > A. graveolens > C. asiatica, whereas total flavonoids order is O. stamineus > S. burahol > P. niruri > A. graveolens > C. asiatica > S. arvensis > C. xanthorrizha > C. domestica. We concluded that O. stamineus was the most suitable herb to be used as a bioreductor in the green synthesis of AgNPs.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: Antioxidant, silver nanoparticles, diabetic wound healing, medicinal plants
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy > Department of Pharmacy
Depositing User: Kartini
Date Deposited: 30 Mar 2020 03:50
Last Modified: 03 Jun 2022 07:48

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