Lorensia, Amelia and Suryadinata, Rivan Virlando and Ratnasari, Richa (2020) Pilot Study of Lung Function Improvement in Peak Expiratory Flow(PEF) Value Using Fish Oil Containing Omega-3 Therapy in Asthma. Global Medical and Health Communication, 8 (3). pp. 211-218. ISSN 2301-9123; eISSN 2460-5441
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Abstract
Fish oil contains omega-3 as an anti-inflammatory effect that can inhibit the production of arachidonic acid 5-lipoxygenase (ALOX5), an enzyme that aggravates the inflammation of the lungs that cause asthma. This study aims to determine the effect of omega-3 from fish oil on improving lung function with peak expiratory flow (PEF) value in patients with outpatient asthma in Surabaya. The research design used in this research is pre-post test design and lung function examination by using a peak flow meter. Then follow up every week for four weeks during the use of fish oil, and the results of his research were analyzed by t test. The study was conducted from April 2017 until January 2018 in Surabaya. The sample of the study was 27 adult asthma patients. The results showed that most of the study subjects had an increase in PEF value every week. Besides, there was a significant increase of PEF values gradually at T0 (before intervention) to T4 (intervention for four weeks), indicating an improved effect after the use of fish oil in a four-week study sample. In conclusion, fish oil containing omega-3 is effective in improving lung function in outpatient asthma patients.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Asthma, fish oil, omega-3, peak expiratory flow |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmacy |
| Depositing User: | Ester Sri W. 196039 |
| Date Deposited: | 04 Jan 2021 04:26 |
| Last Modified: | 05 Jan 2021 08:28 |
| URI: | http://repository.ubaya.ac.id/id/eprint/38698 |
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