Formulation Physical Characteristic of Hard Candy Lozenge of Citrus Limon Essential Oil on Various Types of Sugar Free Candy Base (Isomalt, Mannitol, Sorbitol)

Nawatila, Roisah and Azminah, Azminah (2024) Formulation Physical Characteristic of Hard Candy Lozenge of Citrus Limon Essential Oil on Various Types of Sugar Free Candy Base (Isomalt, Mannitol, Sorbitol). Pharmaceutical Journal of Indonesia, 10 (1). pp. 53-58. ISSN 2461-114XÂ

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Abstract

Citrus limon is a natural ingredient that has potential as an anti-anxiety. The dopamine-enhancing effect on the blood brain barrier due to consuming citrus limon essential oil can help relieve stress, fatigue, dizziness, and anxiety. This study aims to formulate citrus limon essential oil hard candy lozenge with various types of sugar free candy bases and evaluate its effect on the physical characteristic of the lozenge. Previously, this study was preceded by identifying the D-Limonene compounds as an active material on the citrus limon essential oil using the GC-MS method. There are three formulas used in this study, including F1 (isomalt), F2 (mannitol), and F3 (sorbitol). Physical characteristic tests carried out include organoleptic, weight variations, dimension, hardness, friability, dissolved pH, and dissolve time. The identification test of citrus limon essential oil using GC-MS showed the presence of D-Limonene compound. Thus, it can be concluded that the raw material of the oil was in accordance with the established quality. The results of the physical characteristics of the three formulas in the tablet dimension test, hardness, and the dissolved pH met the requirements. In addition, the organoleptic test of F1 and F3 yields better results than F2 (murky white color and rough texture). The evaluation of weight variation, friability, and dissolve time of F1 and F3 met specifications, while F2 did not meet specifications. Therefore, the sugar free candy base that can be developed into a hard candy lozenge in this study was by using isomalt (F1) and sorbitol (F3).

Item Type:	Article
Uncontrolled Keywords:	Citrus Limon, Sugar Free, Hard Candy, Lozenge
Subjects:	Q Science > QC Physics Q Science > QD Chemistry R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	ROISAH NAWATILA
Date Deposited:	25 Feb 2025 05:51
Last Modified:	25 Feb 2025 05:51
URI:	http://repository.ubaya.ac.id/id/eprint/48060

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