Discovery of Novel Alkaloids from Magnolia Genus: A Literature Review from 2002-2024

Yuniarta, Tegar Achsendo and Handayani, Rosita (2025) Discovery of Novel Alkaloids from Magnolia Genus: A Literature Review from 2002-2024. Borneo Journal of Pharmacy, 8 (3). pp. 219-227. ISSN 2621-4814

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Abstract

The genus Magnolia, encompassing hundreds of globally distributed species, has a long-standing history in traditional medicine for treating diverse ailments. These species are particularly renowned for their rich array of bioactive compounds, notably alkaloids. This study provides a comprehensive summary of novel alkaloid compounds identified in various Magnolia species within recent years. Through a targeted literature review utilizing Google Scholar and PubMed (2002–2024), we pinpointed nine novel alkaloids and one nitrogen-based compound isolated from four distinct Magnolia species. These newly discovered compounds exhibited promising bioactivities, including significant antiplatelet and anti-acetylcholinesterase effects. Structurally, the majority of these compounds belong to the aporphine and benzylisoquinoline classes, although some display unique configurations, such as glycosidic or N-oxide alkaloids. This review aims to bridge a critical gap in the existing scientific literature regarding the comprehensive documentation of novel alkaloid secondary metabolites found across the diverse Magnolia genus.

Item Type:	Article
Uncontrolled Keywords:	Alkaloids; Magnolia; Phytochemicals
Subjects:	Q Science > QD Chemistry
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	TEGAR ACHSENDO YUNIARTA
Date Deposited:	01 Sep 2025 05:21
Last Modified:	01 Sep 2025 05:21
URI:	http://repository.ubaya.ac.id/id/eprint/49474

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