Nutraceuticals enhanced by nanotechnology: A new frontier for obesity treatment

Sukweenadhi, Johan and Balusamy, Sri Renukadevi and Vijayalakshmi, Selvakumar and Sundaravadivelu, Sumathi and Huq, Md Amdadul and Nag, Sagnik and Mohanto, Sourav and Oh, Deong Hwan and Perumalsamy, Haribalan (2025) Nutraceuticals enhanced by nanotechnology: A new frontier for obesity treatment. Process Biochemistry, 156. pp. 217-235. ISSN 1873-3298

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Official URL / DOI: https://doi.org/10.1016/j.procbio.2025.05.021

Abstract

Nutraceuticals encompass bioactive compounds like polyphenols, flavonoids, and essential fatty acids inherent in food that play defensive roles against human ailments. Presently, the pharmaceutical industry is focused on nutraceutical-based nanomaterials to mitigate drawbacks in obesity treatment. The use of nanomaterials en hances bioavailability, stability, and targeted drug delivery, diminishing side effects. This review delineates the significance, limitations, and molecular mechanisms of nutraceuticals’ pharmacological properties, emphasizing how nutraceutical-based nanomaterials address challenges for effective obesity treatment. We outline potential nano-based anti-obesity drugs for heightened pharmacological impact and acknowledge associated clinical challenges and limitations. Critically, we evaluate the advantages and disadvantages of nutraceuticals, advo cating various delivery systems to enhance their anti-obesity efficacy. Notably, nutraceutical-based nanoparticles offer increased bioavailability, precise distribution, reduced side effects, and prolonged sustainability, revolu tionizing obesity management. Conscious implementation of nutraceutical-based nanoparticles holds promise in alleviating complications associated with conventional nutraceuticals in obesity management.

Item Type: Article
Uncontrolled Keywords: Nutraceuticals Nano-based anti-obesity drugs Phytochemicals Bioavailability
Subjects: Q Science > Q Science (General)
Q Science > QK Botany
R Medicine > R Medicine (General)
Divisions: Faculty of Technobiology > Department of Biology
Depositing User: JOHAN SUKWEENADHI
Date Deposited: 26 May 2026 03:56
Last Modified: 26 May 2026 03:56
URI: http://repository.ubaya.ac.id/id/eprint/50757

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