Kartini, Kartini (2011) Immunomodulator Activity Of An Isolate From Artocarpus Champeden Spreng. On Cytotoxicity Function Of Cd8+ Of Mice. In: International Seminar On Translational Research In Cancer Chemoprevention, 11 - 12 October 2011, Serpong.
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Abstract
Research of traditional medicine is important to maximize the utilization of natural resources. Artocarpus champeden Spreng. is one of medicinal plants that must be studied because a lot of diseases have been treated traditionally with this plant, such as cancer. Phenolic compounds such as flavonoid, tannin, phenilpropane derivative and simple phenol contained in medicinal plant have been proved for their immunomodulator activity. This study was conducted to explore whether flavonoid of Artocarpus champeden could also increase the activity of immunocompetent cell that play an important role in immunity against cancer especially to Cytotoxic T Lymphocyte (CD8+). Assay of cytotoxicity of CD8+ by MLR (Mixed Lymphocyte Response) showed that DE. 6.4 fraction (contain flavonoids) could not stimulate the activation of CD8+ significantly (p<0.05) at all concentrations compared to the control.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Uncontrolled Keywords: | Artocarpus champeden, flavonoid, CD8+, cytotoxicity, immunomodulator |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmacy |
| Depositing User: | Karyono |
| Date Deposited: | 12 Oct 2012 06:50 |
| Last Modified: | 03 Mar 2020 03:18 |
| URI: | http://repository.ubaya.ac.id/id/eprint/1174 |
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