Ratih, Ratih and Asmari, Mufarreh and El Deeb, Sami (2018) Development of New Monolithic Polysaccharide-Based Columns for HPLC Enantiomeric Separation. In: Books of Abstracts 12th International Symposium on Pharmaceutical Sciences (ISOPS) June 26-29, 2018. Ankara University of Pharmacy Publication, Turkey, pp. 263-265. ISBN 978-975-136-378-3
Preview |
PDF
12th International Syposiumon Pharmaceutical Sciences_Ratih.pdf Download (10MB) | Preview |
Abstract
Chondroitin sulfate A and maltodextrin have been studied as potential chiral selectors to provide new polysaccharide-based chiral stationary phases. A capillary electrophoresis method has been involved to figure out the enantiomers recognition behaviour in the presence of chiral selector. Chondroitin sulfate A 0.3% w/v and maltodextrin 10% w/v which found to be the optimal values in CE were immobilized onto monolithic silica epoxy and monolithic silica amine columns by Schiff base reaction respectively. The immobilized chondroitin sulfate A-based and maltodextrin-based CSPs have shown intial enantiomeric separation of amlodipine and verapamil as model compound of by HPLC.
| Item Type: | Book Section |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmacy |
| Depositing User: | Ester Sri W. 196039 |
| Date Deposited: | 13 Feb 2019 03:19 |
| Last Modified: | 15 Dec 2023 04:58 |
| URI: | http://repository.ubaya.ac.id/id/eprint/34335 |
Actions (login required)
 |
View Item |
