Wirjatmadi, Bambang and Suryadinata, Rivan Virlando (2020) The Alteration on Malondialdehyde Content on Wistar Rats’ Blood and Lungs Tissue to Ward the Exposure of Electric Cigarette Smoke. Indian Journal of Public Health Research & Development, 11 (3). pp. 1881-1887. ISSN 0976-0245(Print); 0976-5506(Electronic)
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Abstract
The effect of electric cigarette smoke exposure had increased due to the number of electric cigarette smoker that raised every year. The smoke which enters the respiratory tract enhance the free radical inside the body, either in blood or lung tissue. The exceeding amount of free radical could trigger the oxidative stress which causes cell damage. The increase of cell damage within lung tissue is accompanied by the enhancement of malondialdehyde content. Therefore, this study aimed to know the malondialdehyde content alteration on blood and lung tissue against the exposure of electric cigarette smoke. This study used experimental methodology with posttest control group design using male Wistar rats as the sample. Wester rats were divided into groups and examined the cell damage through malondialdehyde content within the blood and the malondialdehyde expression within the lung tissue. The exposure of electric cigarette smoke was given to each group with different amount and duration. The lung tissue damage was measured using malondialdehyde content parameter within the blood and immunohistochemistry (IHC) on lung tissue. The finding showed that there was differentiation on malondialdehyde content within the blood and malondialdehyde expression on lung tissue (p< 0.05). Whereas the relation between two groups showed a strong and significant relationship for (r=0.945) and (p=0.000). The duration of electric cigarette smoke exposure could affect the enhancement of malondialdehyde content within the blood and lung tissue.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Malondialdehyde, electric cigarette, immunohistochemistry, lungs tissue |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medical |
| Depositing User: | Ester Sri W. 196039 |
| Date Deposited: | 06 Jul 2020 07:49 |
| Last Modified: | 06 Jul 2020 07:49 |
| URI: | http://repository.ubaya.ac.id/id/eprint/37880 |
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