Evaluasi penggunaan antibiotik profilaksis pada pasien bedah ortopedi di Rumah Sakit Bangil

Firdaus, Yolanda Virgi and Jaelani, Abdul Kadir and Herawati, Fauna and Yulia, Rika (2021) Evaluasi penggunaan antibiotik profilaksis pada pasien bedah ortopedi di Rumah Sakit Bangil. Intisari Sains Medis, 12 (2). pp. 407-414. ISSN 2503-3638, E-ISSN: 2089-9084

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Abstract

Introduction: Trauma to the bones causes fractures and generally increases the risk of infection. To reduce the risk of infection, prophylactic therapy can be given before surgery. Previous studies have suggested that prophylactic antibiotics were irrational and can increase the incidence of antibiotic resistance. This study aims to determine the compatibility of antibiotics prescription for prophylactic fracture surgery based on hospital antibiotics (PPAB) and ASHP guidelines. In addition, this study also determined the quantity of prophylactic antibiotic used. Methods: This was an observational study by taking data from patient medical records and data on antibiotic sales during the period January to November 2020 at Bangil Hospital retrospectively. The data were analyzed descriptively to determine the suitability of the six indicators of accuracy namely right indication, the right type, the right route, the right dose, the right time of administration and the right duration of administration. Antibiotics quantity analyzed quantitatively by using DDD/100 days patient method and DU 90%. Results: A total of 83 samples were obtained by purposive sampling that met the criteria. The evaluation results of the appropriateness of prophylactic antibiotics based on the guidelines were the right type (28.92%), right indication (100%), right dose (55.42%), right route (100%), right duration of administration (66.27%) and right timing of administration (98.80%). Evaluation of the quantity concluded that the total value of DDD was 86.71 DDD/100 days of patients with the highest value on the use of Cefuroxime and Ceftriaxone. Conclusion: The highest use of antibiotics focuses on the use of Cefuroxime and Ceftriaxone. The appropriateness of the use of prophylactic antibiotics in orthopedic surgery patients is the right indication, right route, and right time of administration based on PPAB and ASHP guidelines. The accuracy of the type, dose, and duration of administration still needs to be improved.

Item Type:	Article
Uncontrolled Keywords:	Antibiotic Prophylaxis, Orthopedic Surgery, Fractures, PPAB, DDD / 100 patient days
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Pharmacy > Department of Pharmacy
Depositing User:	Ester Sri W. 196039
Date Deposited:	09 Jun 2021 03:27
Last Modified:	18 Aug 2021 04:02
URI:	http://repository.ubaya.ac.id/id/eprint/39682

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