Ngaliman, Hansen and Raharjo, Dian Natasya and Setiawan, Finna (2023) Antimicrobial Activities of Ethanol Extract from Impatiens balsamina L. Leaves against Paronychia Pathogens. In: The 1st International Conference on Health and Medicine (ICHM 2023): The Island Doctors- Overcoming Challenges for Improved Health, 26-27 July 2023, Ambon, Indonesia. (Unpublished)
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Abstract
Paronychia is the infection of the nail folds due the damage of cuticle which symptoms include pain, itchiness and pus-formation. Acute paronychia caused by Staphylococcus aureus while chronic paronychia caused by Candida albicans. One of the herbal used to treat paronychia empirically is garden balsam leaves (Impatiens balsamina L.). The leaves are expected to contain phenolic and flavonoid compounds which have antimicrobial activity. The aim of this research is to find out the antimicrobial activity of balsam leaves thus herbal medicine can be developed. Antimicrobial assay is carried out on Staphylococcus aureus and Candida albicans. Test material used in this study is extracted with Ultrasonic-Assisted Extraction (UAE) and ethanol 80% as solvent. Antimicrobial assay is carried out with agar-diffusion cylinder-plate method using extract with concentration 6000, 8000, 10000, and 12000 ppm as well as gentamicin and ketoconazole as positive controls. Result shows that the 12000 ppm extract concentration’s antimicrobial activity is similar to gentamicin while the other concentrations have lower antimicrobial activity compared to the positive controls. Determination of the total phenolic and flavonoid content are carried out to calculate the content in the extract and the total phenolic and flavonoid content obtained are 4,07 %GAE and 3,63 %QE respectively. Keywords: Impatiens balsamina, Antimicrobial, Flavonoid, Paronychia, Phenolic
| Item Type: | Conference or Workshop Item (Speech) |
|---|---|
| Uncontrolled Keywords: | Impatiens balsamina, Antimicrobial, Flavonoid, Paronychia, Phenolic |
| Subjects: | Q Science > QR Microbiology R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmacy |
| Depositing User: | DIAN NATASYA R - 210004 |
| Date Deposited: | 02 Aug 2023 04:28 |
| Last Modified: | 27 Sep 2023 04:23 |
| URI: | http://repository.ubaya.ac.id/id/eprint/44631 |
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