Mukadar, Olivia and Irawati, Sylvi and Azminah, Azminah (2025) Essential oils in influencing gene expression involved in hypertension: a Scoping Review. Essential oils in influencing gene expression involved in hypertension: a Scoping Review, 11 (9). ISSN 2460-2582; E-ISSN 2407-795X (In Press)
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Abstract
Hypertension, one of global health problems, is often treated with antihypertensive drugs that may cause adverse drug reactions, thus increasing interests in alternative therapies such as essential oils which are known to have antioxidant and anti-inflammatory properties. This study aimed to assess the effect of essential oils on gene expression involved in the regulation of blood pressure through a scoping review of available research that explore the potential benefit of essential oils as a natural complementary therapy. This study is reported according to PRISMA protocol for scoping review. We have selected 24 relevant articles that were published from 2019- 2024. Thematic analysis was applied to identify important patterns and themes from the published literature to gain in-depth insights into the topic under study. The results showed that essential oils have significant potential benefits in influencing the expression of genes involved in hypertension through antioxidant and anti-inflammatory mechanisms. Compounds such as linalool, eugenol, and allicin play key roles. Analysis of the selected articles showed that essential oils can lower blood pressure by modulating genetic pathways related to oxidative stress and inflammation. This study highlights the potential benefit of essential oils as a natural complementary therapy for hypertension, although the exact mechanisms and effectiveness in larger population still requires further research.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Essential Oil, Gene Expression, Hypertension |
| Subjects: | Q Science > Q Science (General) R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy > Department of Pharmacy |
| Depositing User: | Olivia Onita Sari Mukadar |
| Date Deposited: | 08 Aug 2025 05:30 |
| Last Modified: | 08 Aug 2025 05:30 |
| URI: | http://repository.ubaya.ac.id/id/eprint/49333 |
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